Belinostat injection
Belinostat injection
What is this medicine?
BELINOSTAT (beh-LIH-noh-STAT) is a chemotherapy drug. It is used to treat peripheral T-cell lymphoma.
How should I use this medicine?
This medicine is for infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
dizziness
signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose
signs and symptoms of infection like fever or chills; cough; muscle weakness; sore throat; pain or trouble passing urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; right upper belly pain; yellowing of the eyes or skin
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loose or watery stool
loss of appetite
nausea, vomiting
What may interact with this medicine?
Do not take this medicine with any of the following medications:
atazanavir
This medicine may also interact with the following medications:
erlotinib
gemfibrozil
sorafenib
What if I miss a dose?
It is important not to miss a dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
infection
kidney disease
liver disease
low blood counts, like low white cell, platelet, or red cell counts
an unusual or allergic reaction to belinostat, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Do not breast-feed an infant while taking this medicine or for 2 weeks after the last dose.
This medicine may interfere with the ability to have or father a child. Talk with your doctor or health care professional if you are concerned about your fertility.
Updated:  
January 17, 2020