Becaplermin, rh-PDGF skin gel

July 17, 2018

Becaplermin, rh-PDGF skin gel

What is this medicine?

BECAPLERMIN (be KAP ler min) is used on the skin to treat ulcers on the lower legs in patients with diabetes.

How should I use this medicine?

This medicine is for external use only. Follow the directions on the prescription label. Wash your hands before use. Squeeze the prescribed amount of gel onto a clean, non-absorbable surface like wax paper. With a cotton swab, tongue depressor, or a similar application aid, spread an even layer of the gel over the ulcer. Cover the ulcer with a saline-moistened gauze dressing. After 12 hours, remove the gauze dressing and rinse the ulcer with saline or water to remove excess gel. Apply a new piece of saline-moistened gauze dressing to the ulcer. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • reddened skin near ulcer

What may interact with this medicine?

Interactions are not expected. Do not use any other skin products on the treated area without asking your doctor or health care professional.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F). Do not freeze. Throw away any unused portion after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • cancer at the site of the ulcer

  • wounds that are closed by your health care professional

  • wounds that show exposed joints, tendons, ligaments, or bone

  • an unusual or allergic reaction to becaplermin, parabens, metacresol, or other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Your doctor or health care professional may change your dose weekly or every other week as the size of your ulcer changes. If your skin ulcer does not get smaller in 10 weeks or does not get better after 20 weeks, ask your doctor or health care professional if you should continue using this medicine.

This medicine works best when used with other methods for good skin ulcer care such as not bearing weight on the leg that has the skin ulcer.


July 17, 2018