Baclofen injection for intrathecal use
Baclofen injection for intrathecal use
What is this medicine?
BACLOFEN (BAK loe fen) is a muscle relaxer. It is used to treat severe spasms.
How should I use this medicine?
This medicine is for injection into the space around the spinal cord. It can be given by a health care professional in a clinic or hospital setting. Patients can also have a pump implanted into their back for a continuous infusion.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 years old for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in emotions or moods
changes in vision
chest pain
fast, irregular heartbeat
feeling faint or lightheaded, falls
hallucinations
loss of balance or coordination
ringing of the ears
seizures
trouble passing urine or change in the amount of urine
trouble walking
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste
confusion
constipation
diarrhea
dry mouth
headache
muscle weakness
nausea, vomiting
trouble sleeping
What may interact with this medicine?
Do not take this medication with any of the following medicines:
narcotic medicines for cough
This medicine may also interact with the following medications:
alcohol
antihistamines for allergy, cough and cold
certain medicines for anxiety or sleep
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for seizures like phenobarbital, primidone
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
local anesthetics like lidocaine, pramoxine, tetracaine
medicines that relax muscles for surgery
narcotic medicines for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
What if I miss a dose?
It is important to keep your appointments to have this medicine administered or to refill your pump. If you cannot make your appointment, contact your health care provider to make other arrangements.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bleeding disorders
diabetes
mental illness
kidney disease
recent stroke
seizures
an unusual or allergic reaction to baclofen, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.
Do not suddenly stop taking your medicine. If you do, you may develop a severe reaction. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects. Follow the advice of your doctor.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
Updated:  
July 17, 2018