What is this medicine?
ATAZANAVIR (at a za NA veer) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blood in the urine
feeling faint or lightheaded, falls
irregular heart rate
pain in the lower back or side
pain when urinating
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of infection like fever or chills; cough; or sore throat
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea or vomiting; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
tingling or burning in your hands, feet or around the mouth
weight gain around waist, back, or thinning of face, arms, legs
What may interact with this medicine?
Do not take this medicine with any of the following medications:
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
red yeast rice
sildenafil (when given as Revatio for treatment of pulmonary arterial hypertension)
St. John's wort
This medicine may also interact with the following medications:
antacids or buffered medications
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for cholesterol like atorvastatin or rosuvastatin
certain medicines for depression, anxiety, or psychotic disturbances like lurasidone and quetiapine
certain medicines for erectile dysfunction
certain medicines for fungal infections like ketoconazole, itraconazole, posaconazole, and voriconazole
certain medicines for seizures like carbamazepine, lamotrigine, phenobarbital, phenytoin
certain medicines for stomach problems like cimetidine, famotidine, omeprazole, lansoprazole
female hormones, like estrogens and progestins and birth control pills
other medicines for HIV
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store tightly closed at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Dispose of unused medicines through community take-back disposal programs when available or place this medicine in an unrecognizable, closed container in the household trash.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an unusual or allergic reaction to atazanavir, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
This medicine may affect how well your kidneys work. Drink plenty of fluids while taking this medicine to stay hydrated.
November 11, 2018