Dextromethorphan; Promethazine oral solution
Text SUPPORT1 to 21825 to learn if you may be eligible for financial support with your medication(s).
Msg & Data Rates May Apply. Msg freq varies. Terms apply. Text HELP for help. Text STOP to end.
Dextromethorphan; Promethazine oral solution
What is this medicine?
DEXTROMETHORPHAN; PROMETHAZINE (dex troe meth OR fan; proe METH a zeen) is a cough suppressant and an antihistamine. It is used to treat coughing due to colds or allergies. This medicine will not treat an infection.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Use a specially marked spoon or container to measure your medicine. Household spoons are not accurate. Take your doses at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. Do not use this medicine in children less than 2 years of age.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
confusion
fever, chills, sore throat
restlessness
seizures
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
trouble passing urine or change in the amount of urine
trouble swallowing
uncontrollable movements of the arms, face, head, mouth, neck, or upper body
unusual bruising or bleeding
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
drowsiness
dizziness
dry mouth
nausea
upset stomach
What may interact with this medicine?
Do not take this medicine with any of the following medications:
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
alcohol or alcohol-containing products
antihistamines for allergy, cough, and cold
atropine
certain medicines for anxiety or sleep
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
epinephrine
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
ipratropium
medicines for depression, anxiety or psychotic disturbances
medicines for high blood pressure
medicines for seizures like phenobarbital, primidone, phenytoin
medicines that relax muscles for surgery
metoclopramide
narcotic medicines for pain
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of the following conditions:
blockage in your bowel
diabetes
eczema
glaucoma
heart disease
liver disease
low blood counts, like low white cell, platelet, or red cell counts
lung or breathing disease, like asthma
Parkinson's disease
prostate disease
seizures
stomach or intestine problems
trouble passing urine
an unusual or allergic reaction to promethazine, dextromethorphan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your doctor if your symptoms do not improve or if they get worse.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Updated:  
October 30, 2020