Lansoprazole; Amoxicillin; Clarithromycin Tablets and Capsules
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Lansoprazole; Amoxicillin; Clarithromycin Tablets and Capsules
What is this medicine?
LANSOPRAZOLE; AMOXICILLIN; CLARITHROMYCIN (lan SOE pra zole; a mox i SIL in; kla RITH roe mye sin) is a combination of three medicines used to treat ulcers associated with a bacterial infection.
How should I use this medicine?
Take these medicines by mouth with a full glass of water. Each dose should be taken twice per day before eating. Follow the directions on the prescription label. Do not crush or chew. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not skip doses or stop your medicine early even if you feel better. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
bloody or watery diarrhea
breathing problems
confusion
dizziness
rash, fever, and swollen lymph nodes
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
stomach polyps
vaginal discharge, itching, or odor in women
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste
diarrhea
dry mouth, thirst
headache
mouth sores
muscle pain
nausea, vomiting
stomach pain
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for cholesterol like cerivastatin, lovastatin, simvastatin
certain medicines for HIV or AIDS like atazanavir, nelfinavir, rilpivirine, saquinavir
cisapride
conivaptan
dihydroergotamine, ergotamine
dofetilide
dronedarone
eletriptan
eplerenone
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
flibanserin
ivabradine
lomitapide
lurasidone
naloxegol
pimozide
posaconazole
ranolazine
silodosin
tolvaptan
red yeast rice
thioridazine
ziprasidone
This medicine may also interact with the following medications:
alfentanil
bromocriptine
certain medicines for anxiety or sleep
certain medicines for blood pressure
certain medicines for diabetes
certain medicines for erectile dysfunction
certain medicines for fungal infections
certain medicines for irregular heart beat
certain medicines for seizures
certain medicines that treat or prevent blood clots like warfarin
cilostazol
colchicine
cyclosporine
digoxin
disopyramide
erlotinib
female hormones, like estrogens or progestins and birth control pills
iron supplements
methotrexate
methylprednisolone
mycophenolate
other medicines for cholesterol
other medicines for HIV or AIDS
other medicines for infections
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
St. John's Wort
sucralfate
tacrolimus
theophylline
tolterodine
vinblastine
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
history of irregular heartbeat
kidney disease
liver disease
lupus
myasthenia gravis
an unusual or allergic reaction to lansoprazole, amoxicillin, clarithromycin, other antibiotics, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care provider for regular check ups. Tell your doctor or if your symptoms do not improve or if they get worse.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Call your doctor as soon as you can if you get a fever, watery diarrhea, stomach pain, or vomiting. These could be symptoms of a more serious illness. Do not treat yourself. Call your doctor for advice.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.
If you are diabetic you may get a false-positive result for sugar in your urine. Talk to your health care provider.
This medicine may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care provider.
Updated:  
November 11, 2020