Amoxicillin Trihydrate Oral capsule, Clarithromycin Oral tablet, Omeprazole Oral capsule, gastro-resistant sprinkles

What is this medicine?

AMOXICILLIN; CLARITHROMYCIN; OMEPRAZOLE (a mox i SIL in; kla RITH roe mye sin; oh ME pra zol) is a combination of three medicines used to treat ulcers associated with a bacterial infection.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• any chronic illness

• kidney disease

• liver disease

• an unusual or allergic reaction to amoxicillin, clarithromycin, omeprazole, other antibiotics, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Take these medicines by mouth with a full glass of water. Each dose should be taken twice per day before eating. Follow the directions on the prescription label. Swallow the capsules and tablets whole. Do not crush or chew. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not skip doses or stop your medicine early even if you feel better. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• atazanavir

• cisapride

• colchicine

• dihydroergotamine

• ergotamine

• some heart medicines like amiodarone, bepridil, dofetilide, droperidol, flecainide, ibutilide, procainamide, quinidine, sotalol

• some medicines for cholesterol like cerivastatin, lovastatin, simvastatin

• medicines for sleep or anxiety, like alprazolam, triazolam or midazolam

• nelfinavir

• pimozide

• red yeast rice

• rifampin

• St. John's wort

This medicine may also interact with the following medications:

• carbamazepine

• cilostazol

• cyclosporine

• digoxin

• diltiazem

• disulfiram

• female hormones, like estrogens or progestins and birth control pills

• iron supplements

• other antibiotics

• other medicines for depression, sleep or psychotic disturbances

• probenecid

• sildenafil

• some medicines for fungal infections like itraconazole, ketoconazole

• some medicines for HIV-infection or AIDS

• tacrolimus

• theophylline

• warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. Tell your doctor or if your symptoms do not improve or if they get worse.

Call your doctor as soon as you can if you get a fever, watery diarrhea, stomach pain, or vomiting. These could be symptoms of a more serious illness. Do not treat yourself. Call your doctor for advice.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

If you are diabetic you may get a false-positive result for sugar in your urine. Talk to your health care provider.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• bloody or watery diarrhea

• bone, muscle or joint pain

• breathing problems

• dizzy, confused

• fever, chills

• redness, blistering, peeling or loosening of the skin, including inside the mouth

• stomach pain, cramps

• trouble passing urine or change in the amount of urine

• unusual bleeding, bruising

• unusually weak or tired

• vaginal itching, discharge

• vomiting

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

• diarrhea

• dry mouth, thirst

• headache

• loss of appetite

• stomach upset, nausea

• unusual taste

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.