Aliskiren; Hydrochlorothiazide, HCTZ Tablet
Text SUPPORT1 to 21825 to learn if you may be eligible for financial support with your medication(s).
Msg & Data Rates May Apply. Msg freq varies. Terms apply. Text HELP for help. Text STOP to end.
Aliskiren; Hydrochlorothiazide, HCTZ Tablet
What is this medicine?
ALISKIREN; HYDROCHLOROTHIAZIDE (a lis KYE ren; hye droe klor oh THYE a zide) is a combination of a renin inhibitor and a diuretic. It treats high blood pressure.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on your prescription label. You can take this medicine with or without food. However, you should always take it the same way each time. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your health care provider about the use of this drug in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or hives, swelling of the hands, feet, face, lips, throat, or tongue
breathing problems
changes in vision
eye pain
fast, irregular heartbeat
feeling faint or lightheaded, falls
fever or sore throat
gout pain
low blood pressure
muscle pain or cramps
pain, tingling, numbness in the hands or feet
pain or difficulty passing urine
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
cough
diarrhea
dizziness
dry mouth
flu-like symptoms
headache
stomach upset
What may interact with this medicine?
alcohol
atorvastatin
barbiturates
cholestyramine
colestipol
digoxin
dofetilide
furosemide
irbesartan
lithium
medicines for blood pressure
medicines for diabetes
medicines for fungal infections like ketoconazole
medicines that relax muscles for surgery
narcotic medicines for pain
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
potassium supplements
steroid medicines like prednisone or cortisone
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Do not throw out the packet in the container. It keeps the medicine dry. Throw away any unused drug after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
dehydration
diabetes
gout
kidney disease or kidney stones
liver disease
pancreatitis
small amount of urine or difficulty passing urine
an unusual or allergic reaction to aliskiren, hydrochlorothiazide, HCTZ, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your health care provider for regular checks on your progress. Check your blood pressure as directed. Ask your health care provider what your blood pressure should be. Also, find out when you should contact him or her.
Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child, especially in the second or third trimester. Talk to your health care provider for more information.
This drug may increase your blood sugar. Ask your health care provider if changes in diet or drugs are needed if you have diabetes.
If you have diabetes and take a drug known as an ACE inhibitor or ARB, do not take this drug. Talk to your health care provider if questions.
Do not treat yourself for coughs, colds, or pain while you are using this drug without asking your health care provider for advice. Some drugs may increase your blood pressure.
Check with your doctor or health care provider if you get an attack of severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this drug.
Avoid salt substitutes unless you are told otherwise by your health care provider. Talk to your health care provider about other dietary needs.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this drug. Avoid alcoholic drinks.
Talk to your health care provider about your risk of skin cancer. You may be more at risk for skin cancer if you take this drug.
This drug can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing, and use sunscreen. Do not use sun lamps or tanning beds/booths.
Updated:  
October 08, 2020