Agalsidase Beta injection

What is this medicine?

AGALSIDASE BETA is used to replace an enzyme that is missing in patients with Fabry disease. It is not a cure.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• chest pain, tightness

• depression

• dizziness

• fast, irregular heart beat

• swelling of the arms or legs

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• aches or pains

• anxiety

• fever or chills at the time of injection

• headache

• nausea, vomiting

• stomach pain, upset

What may interact with this medicine?

• amiodarone

• chloroquine

• gentamicin

• hydroxychloroquine

• monobenzone

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• heart disease

• an unusual or allergic reaction to agalsidase beta, mannitol, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

There is a registry for patients with Fabry disease. The registry is used to gather information about the disease and its effects. Talk to your health care provider if you would like to join the registry.