These medicines are called nicotine-replacement therapy. They ease withdrawal symptoms and reduce the craving for nicotine, the National Cancer Institute (NCI) says. People trying to quit get a dose of nicotine but not by smoking. Because it is cigarette smoke that harms the lungs, a smoker's health begins to get better during this treatment. Smokers should use these drugs in smaller and smaller amounts for a few months, then finally stop using them. Bupropion and varenicline tartrate are 2 smoking-cessation aids that do not contain nicotine.

You should also check with your health care provider if you're pregnant or breastfeeding, or if you have any history of cardiovascular disease.

Nicotine-replacement therapy is available without a prescription as a patch, gum, nasal spray, inhaler, and lozenge. You should choose an aid that best fits your lifestyle and your need for nicotine. Other help for smoking cessation, such as counseling, hypnosis, and acupuncture, is also available.

The inhaler resembles a cigarette and contains a cartridge. You can draw a small amount of nicotine into your mouth with each puff. The nicotine does not end up in your lungs, as it does in smoking. It is absorbed by the mucus membranes in your mouth and throat.

Each nasal spray contains a certain dose of nicotine. If you have a nasal or sinus condition, or allergies or asthma, you shouldn't use a nicotine nasal spray. This treatment should not be used by young smokers, according to the NCI.

The patches are available with different amounts of nicotine. Once you put the patch on your skin, you leave it on for 16 to 24 hours. As treatment progresses, you use a patch containing less nicotine. Nicotine patch for some people who have skin problems or allergies to adhesive tape, the NCI says.

This treatment is a good choice if you crave having something in your mouth. The gum is available in 2-mg and 4-mg strengths. If you have a jaw joint disease, gum disease, or peptic ulcer disease, you may not want to use nicotine gum. You also shouldn't use the gum if you have dentures or bridges. Nicotine gum also can be used along with the nicotine patch.

Bupropion eases withdrawal symptoms and the urge to smoke, but it does not contain nicotine. Common side effects of this drug are dry mouth, difficulty sleeping, dizziness, and skin rash. If you have a seizure disorder or an eating disorder, you should not use this drug. You also shouldn't use it if you use other medicines that contain bupropion hydrochloride. Varenicline tartrate is another medicine than can help you quit smoking. It may cause serious side effects such as depression and suicidal thoughts or attempts. It also may cause seizures, hostility, and agitation. You may also have problems sleeping. You should not drink alcohol while taking this drug because it may cause unusual behavior or aggressiveness.

Although you shouldn't smoke while using nicotine replacement, if you do, you shouldn’t remove your patch. It’s much more risky that a person will have one cigarette and give up on the replacement therapy, thinking he or she can’t do both.

Your health care provider, dentist, or pharmacist can counsel you on quitting smoking. You can also call a "quitline," a toll-free number that connects you to a telephone counselor.