Hydrocortisone; Neomycin; Polymyxin B
Hydrocortisone Acetate, Neomycin Sulfate, Polymyxin B Sulfate Topical cream
What is this medicine?
HYDROCORTISONE; NEOMYCIN; POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) helps to reduce swelling, redness, and itching of the skin. It is also used to treat skin infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any active infection including active cold sores
kidney disease
large areas of burned or damaged skin
skin wasting or thinning
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, corticosteroids, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for external use only. Do not take by mouth. Follow the directions on the prescription label. Wash your hands before and after use. Apply a thin film of medicine to the affected area. Do not cover with a bandage or dressing unless your doctor or health care professional tells you to. Do not use on healthy skin or over large areas of skin. Do not get this medicine in your eyes. If you do, rinse out with plenty of cool tap water. It is important not to use more medicine than prescribed. Do not use your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use any other skin products without telling your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Do not use for more than 7 days. Tell your doctor or health care professional if you are exposed to anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.
To prevent the spread of infection, do not share skin products, or share towels and washcloths with anyone else. Throw away any unused cream.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
red, itchy, dry scaly skin at the affected site
swelling at the affected site
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
burning or stinging
loss of skin color
streaks in the skin
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Hydrocortisone, Neomycin Sulfate, Polymyxin B Sulfate Ophthalmic drops, suspension
What is this medicine?
HYDROCORTISONE; NEOMYCIN; POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat eye infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infection
contact lens wearer
glaucoma
recent cataract surgery
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, corticosteroids, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Shake well before using. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if think your condition is better. Do not stop using except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use any other eye products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Check with your doctor or health care professional if your condition does not get better after 2 days, or if it gets worse. Do not use longer than 10 days unless instructed by your doctor or health care professional.
Tell your doctor or health care professional if you are exposed to anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.
If you are a contact lens wearer, ask your doctor or health care professional when you can use your lenses again.
A burning or stinging reaction that does not go away may mean you are allergic to this product. Stop using and call your doctor or health care professional.
This medicine can make certain eye conditions worse. Only use it for conditions for which your doctor or health care professional has prescribed.
To prevent the spread of infection, do not share eye products, towels, and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
burning, stinging or swelling of the eyelids
eye pain, decreased, or blurred vision (that will not go away)
rash
watery eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
eye irritation, itching
mild burning, redness or stinging in the eye
temporary watering or blurring of vision
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Store suspension upright. Throw away any unused medicine after the expiration date.
Hydrocortisone, Neomycin Sulfate, Polymyxin B Sulfate Otic drops, solution
What is this medicine?
HYDROCORTISONE; NEOMYCIN; and POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat ear infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infections
chronic ear infections or fluid in the ear
perforated ear drum
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the ears. Follow the directions on the prescription label. Wash hands before and after use. Clean your ear of any fluid that can be easily removed. Do not insert any object or swab into the ear canal. Gently warm the bottle by holding it in the hand for 1 to 2 minutes. Lie down on your side with the infected ear facing upward. Try not to touch the tip of the dropper to your ear, fingertips, or other surface. Squeeze the bottle gently to put the prescribed number of drops in the ear canal. Stay in this position for 30 to 60 seconds to help the drops soak into the ear. Repeat the steps for the other ear if both ears are infected. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not take double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use other ear products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your ear infection does not get better in a few days. Do not use longer than 10 days unless instructed by your doctor or health care professional.
If rash or allergic reaction occurs, stop the product immediately and contact your physician.
It is important that you keep the infected ear(s) clean and dry. When bathing, try not to get the infected ear(s) wet. Do not go swimming unless your doctor or health care professional has told you otherwise.
To prevent the spread of infection, do not share ear products, or share towels and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
rash
red, itchy, dry scaly skin at the affected site
worsening ear pain
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
abnormal sensation in the ear
burning or stinging while putting the drops in the ear
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Hydrocortisone, Neomycin Sulfate, Polymyxin B Sulfate Otic drops, suspension
What is this medicine?
HYDROCORTISONE; NEOMYCIN; and POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat ear infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infections
chronic ear infections or fluid in the ear
perforated ear drum
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the ears. Wash your hands with soap and water. Clean your ear of any fluid that can be easily removed. Do not insert any object or swab into the ear canal. Gently warm the bottle by holding it in the hand for 1 to 2 minutes. Lie down on your side with the infected ear up. Try not to touch the tip of the dropper to your ear, fingertips, or other surface. Shake the bottle immediately before using. Squeeze the bottle gently to put the prescribed number of drops in the ear canal. Stay in this position for 30 to 60 seconds to help the drops soak into the ear. Repeat the steps for the other ear if both ears are infected. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not take double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use other ear products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your ear infection does not get better in a few days. Do not use longer than 10 days unless instructed by your doctor or health care professional.
If rash or allergic reaction occurs, stop the product immediately and contact your physician.
It is important that you keep the infected ear(s) clean and dry. When bathing, try not to get the infected ear(s) wet. Do not go swimming unless your doctor or health care professional has told you otherwise.
To prevent the spread of infection, do not share ear products, or share towels and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
rash
red, itchy, dry scaly skin at the affected site
worsening ear pain
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
abnormal sensation in the ear
burning or stinging while putting the drops in the ear
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Neomycin, Polymyxin B, Hydrocortisone Ophthalmic drops, suspension
What is this medicine?
HYDROCORTISONE; NEOMYCIN; POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat eye infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infection
contact lens wearer
glaucoma
recent cataract surgery
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, corticosteroids, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Shake well before using. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if think your condition is better. Do not stop using except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use any other eye products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Check with your doctor or health care professional if your condition does not get better after 2 days, or if it gets worse. Do not use longer than 10 days unless instructed by your doctor or health care professional.
Tell your doctor or health care professional if you are exposed to anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.
If you are a contact lens wearer, ask your doctor or health care professional when you can use your lenses again.
A burning or stinging reaction that does not go away may mean you are allergic to this product. Stop using and call your doctor or health care professional.
This medicine can make certain eye conditions worse. Only use it for conditions for which your doctor or health care professional has prescribed.
To prevent the spread of infection, do not share eye products, towels, and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
burning, stinging or swelling of the eyelids
eye pain, decreased, or blurred vision (that will not go away)
rash
watery eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
eye irritation, itching
mild burning, redness or stinging in the eye
temporary watering or blurring of vision
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Store suspension upright. Throw away any unused medicine after the expiration date.
Neomycin, Polymyxin B, Hydrocortisone Otic drops, solution
What is this medicine?
HYDROCORTISONE; NEOMYCIN; and POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat ear infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infections
chronic ear infections or fluid in the ear
perforated ear drum
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the ears. Follow the directions on the prescription label. Wash hands before and after use. Clean your ear of any fluid that can be easily removed. Do not insert any object or swab into the ear canal. Gently warm the bottle by holding it in the hand for 1 to 2 minutes. Lie down on your side with the infected ear facing upward. Try not to touch the tip of the dropper to your ear, fingertips, or other surface. Squeeze the bottle gently to put the prescribed number of drops in the ear canal. Stay in this position for 30 to 60 seconds to help the drops soak into the ear. Repeat the steps for the other ear if both ears are infected. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not take double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use other ear products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your ear infection does not get better in a few days. Do not use longer than 10 days unless instructed by your doctor or health care professional.
If rash or allergic reaction occurs, stop the product immediately and contact your physician.
It is important that you keep the infected ear(s) clean and dry. When bathing, try not to get the infected ear(s) wet. Do not go swimming unless your doctor or health care professional has told you otherwise.
To prevent the spread of infection, do not share ear products, or share towels and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
rash
red, itchy, dry scaly skin at the affected site
worsening ear pain
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
abnormal sensation in the ear
burning or stinging while putting the drops in the ear
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Neomycin, Polymyxin B, Hydrocortisone Otic drops, suspension
What is this medicine?
HYDROCORTISONE; NEOMYCIN; and POLYMYXIN B (hye droe KOR ti sone; nee oh MYE sin; pol i MIX in B) is used to treat ear infections.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
any other active infections
chronic ear infections or fluid in the ear
perforated ear drum
an unusual or allergic reaction to hydrocortisone, neomycin, polymyxin B, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is only for use in the ears. Wash your hands with soap and water. Clean your ear of any fluid that can be easily removed. Do not insert any object or swab into the ear canal. Gently warm the bottle by holding it in the hand for 1 to 2 minutes. Lie down on your side with the infected ear up. Try not to touch the tip of the dropper to your ear, fingertips, or other surface. Shake the bottle immediately before using. Squeeze the bottle gently to put the prescribed number of drops in the ear canal. Stay in this position for 30 to 60 seconds to help the drops soak into the ear. Repeat the steps for the other ear if both ears are infected. Do not use your medicine more often than directed. Finish the full course of medicine prescribed by your doctor or health care professional even if you think your condition is better.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not take double or extra doses.
What may interact with this medicine?
Interactions are not expected. Do not use other ear products without talking to your doctor or health care professional.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your ear infection does not get better in a few days. Do not use longer than 10 days unless instructed by your doctor or health care professional.
If rash or allergic reaction occurs, stop the product immediately and contact your physician.
It is important that you keep the infected ear(s) clean and dry. When bathing, try not to get the infected ear(s) wet. Do not go swimming unless your doctor or health care professional has told you otherwise.
To prevent the spread of infection, do not share ear products, or share towels and washcloths with anyone else.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
rash
red, itchy, dry scaly skin at the affected site
worsening ear pain
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
abnormal sensation in the ear
burning or stinging while putting the drops in the ear
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert