Enzalutamide capsules
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Enzalutamide capsules
What is this medicine?
ENZALUTAMIDE blocks the effect of the male hormone called testosterone. This medicine is used for certain types of prostate cancer.
How should I use this medicine?
Take this medicine by mouth with a glass of water. You can take it with or without food. If it upsets your stomach, take it with food. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
chest pain or tightness
confusion
falls
loss of memory
seizures
sudden numbness or weakness of the face, arm or leg
trouble speaking or understanding
trouble walking, dizziness, loss of balance or coordination
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
blood in the urine
breathing problems
diarrhea
dizziness
headache
joint pain
pain, tingling, numbness in the hands or feet
swelling of the ankles, feet, hands
unusually weak or tired
What may interact with this medicine?
Do not take this medicine with any of the following medications:
artemether
certain antivirals for HIV or hepatitis like atazanavir, daclatasvir, doravirine, elbasvir; grazoprevir, fostemsavir, lopinavir, nelfinavir, paritaprevir, rilpivirine, ritonavir, and tipranavir
certain medicines for fungal infections like isavuconazonium and voriconazole
lorlatinib
lurasidone
praziquantel
ranolazine
This medicine may interact with the following medications:
alfentanil
bosentan
certain medications for seizures like carbamazepine, phenobarbital, and phenytoin
cyclosporine
dihydroergotamine
efavirenz
ergotamine
etravirine
fentanyl
gemfibrozil
midazolam
modafinil
nafcillin
omeprazole
pimozide
quinidine
rifabutin
rifampin
rifapentine
St. John's Wort
sirolimus
tacrolimus
warfarin
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose and skip your missed dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bone problems
brain tumor
head injury
heart disease
history of stroke
seizures
an unusual or allergic reaction to enzalutamide, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
This medicine should not be used in women. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
Due to a risk of seizures with enzalutamide therapy, use caution when engaging in activities that could result in serious harm to yourself or others if you pass out.
Updated:  
November 22, 2020