What is this medicine?
TOLVAPTAN (tol VAP tan) is used to treat low levels of sodium in the blood.
How should I use this medicine?
Take this medicine by mouth with a glass of water. This medicine will be started in a hospital. You may need to continue this medicine at home. Follow the directions on the prescription label. Do not stop and re-start this medicine on your own. You may need to go back to a hospital to re-start this medicine. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black or tarry stools
fast, irregular heartbeat
uncontrollable body movements
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
increased hunger or thirst
What may interact with this medicine?
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
medicines for blood pressure
medicines for seizures like carbamazepine, phenobarbital, phenytoin
medicines for tuberculosis like rifampin, rifabutin, and rifapentine
some medicines for fungal infections like fluconazole, miconazole, voriconazole
St. John's Wort
What if I miss a dose?
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
can not feel if you are thirsty
diarrhea or vomiting
if you frequently drink alcohol containing drinks
kidney disease and your body can not make urine
not eaten enough for a long period of time (malnourished)
an unusual or allergic reaction to tolvaptan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
To prevent dehydration, have water available to drink at all times while taking this medicine. Drink when you are thirsty, unless your doctor or healthcare professional tells you otherwise.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
September 30, 2017