March 21, 2017

Terfenadine tablets

What are terfenadine tablets?

TERFENADINE (Seldane®) was an antihistamine. Terfenadine reduced allergy symptoms of hay fever (seasonal allergic rhinitis).

NOTE: This drug is discontinued in the United States.

What should my health care professional know before I take terfenadine?

They need to know if you have any of these conditions:

  • asthma,

  • high blood pressure or heart disease

  • kidney disease

  • liver disease

  • other chronic illness

  • an unusual or allergic reaction to terfenadine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I take this medicine?

Take terfenadine tablets by mouth. Follow the directions on the prescription label. Take terfenadine 1 to 2 hours before or at least 2 hours after eating; taking it with food can make it less effective. Take your doses at regular intervals. Do not take terfenadine more often than directed. You may need to take it for several days as prescribed before your symptoms improve.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with terfenadine?

  • bepridil

  • bosentan

  • carbamazepine

  • cisapride

  • certain antibiotics (clarithromycin, erythromycin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin)

  • fluvoxamine

  • grapefruit juice

  • haloperidol

  • itraconazole

  • ketoconazole

  • medicines for mental depression or other mental disorders

  • medicines to control heart rhythm

  • mibefradil

  • pimozide

  • sotalol

  • thioridazine

  • voriconazole

  • water pills

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking terfenadine?

Tell your prescriber or health care professional if your symptoms do not improve in 1 or 2 days.

Call your prescriber or health care professional if you faint or notice an uneven heart beat.

Terfenadine causes less drowsiness than most other antihistamines. Until you know if it makes you drowsy or dizzy, do not drive, use machinery, or do anything that needs mental alertness.

Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine may make your mouth dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.

What side effects may I notice from taking terfenadine?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • blurred vision

  • fainting spells

  • irregular heartbeat, palpitations, or chest pain

  • seizures (convulsions)

Call your prescriber or health care professional as soon as possible if you get any of these side effects.

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • drowsiness, dizziness

  • dry mouth

  • headache

  • increased appetite or weight gain

  • nausea, vomiting

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and temperatures above 40 degrees C (104 degrees F). Throw away any unused medicine after the expiration date.


March 21, 2017


U.S. FDA-approved Package Insert