Romidepsin injection
Romidepsin injection
What is this medicine?
ROMIDEPSIN (ROE mi DEP sin) is a chemotherapy drug. It is used to treat cutaneous T-cell lymphoma or peripheral T-cell lymphoma.
How should I use this medicine?
This medicine is for infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain
cough
fast, irregular heartbeat
feeling faint or lightheaded, falls
fever or chills, sore throat
shortness of breath
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
loss of appetite
nausea, vomiting
What may interact with this medicine?
antiviral medications for HIV or AIDS
birth control pills
dexamethasone
medicines for fungal infections like ketoconazole and itraconazole
medicines for irregular heart beat like amiodarone, bepridil, dofetilide, encainide, flecainide, propafenone, quinidine
medicines for seizures like carbamazepine, phenobarbital, phenytoin
medicines for tuberculosis
St. John's Wort
warfarin
What if I miss a dose?
It is important not to miss a dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
kidney disease
liver disease
low or high levels of potassium or magnesium in the blood
an unusual or allergic reaction to romidepsin, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for at least 1 month after stopping it. Women should inform their healthcare professional if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine or for at least 1 month after stopping it. There is a potential for serious effects to an unborn child. Talk to your healthcare professional for more information.
Do not breast-feed an infant while taking this medicine or for at least 1 week after stopping it.
This medicine may make it more difficult to get pregnant or to father a child. Talk to your healthcare professional if you are concerned about your fertility.
Updated:  
December 09, 2018