Progesterone vaginal suppositories
Progesterone vaginal suppositories
What is this medicine?
PROGESTERONE (proe JES ter one) is a female hormone. This medicine is used to treat infertility and to prevent miscarriage in women with a condition called corpus luteum insufficiency. This medicine may also be used to prevent preterm delivery in some women. The suppositories are only available when compounded by your pharmacist.
How should I use this medicine?
This medicine is for vaginal use only. Do not take by mouth. Follow the directions on the prescription label. Wash your hands before and after use. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
abnormal vaginal bleeding
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breast tissue changes or discharge
changes in vision
chest pain
confusion
dark urine
general ill feeling or flu-like symptoms
light-colored stools
loss of appetite, nausea
pain, swelling, warmth in the leg
right upper belly pain
problems with balance, talking, walking
severe headaches
shortness of breath
sudden numbness or weakness of the face, arm or leg
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
back pain
depressed mood or mood swings
increased appetite
fluid retention and swelling
nausea, vomiting
stomach cramps or bloating
What may interact with this medicine?
Interactions are not expected. Do not use any other vaginal products without asking your doctor or health care professional.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Protect from light. Keep this medicine in the orginal container until ready to use. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood vessel disease, blood clotting disorder, or suffered a stroke
breast, cervical or vaginal cancer
heart disease
kidney disease
liver disease
miscarriage or abortion
vaginal bleeding
an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress.
If your doctor or health care professional instructs you to use any other medicines in the vagina while you are using this medicine, you should separate the doses by at least 6 hours.
You may notice a white discharge of medicine while using this medicine. This is normal. If it becomes bothersome, contact your doctor or health care professional.
Updated:  
July 17, 2018