Methylene Blue Oral tablet

What is this medicine?

METHYLENE BLUE (METH uh leen bloo) is a dye that is used in certain diagnostic procedures.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• cyanide poisoning

• glucose-6-phosphate dehydrogenase (G6PD) deficiency

• kidney disease

• an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take after meals. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• bupropion

• certain medicines for depression or anxiety

• clomipramine

• doxepin

• duloxetine

• fluoxetine

• MAOIs like Marplan, Nardil, and Parnate

• milnacipran

• mirtazapine

• rasagiline

• selegiline

• St. John's wort

• trazodone

• tryptophan

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• bladder irritation

• fever

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blue-green coloration of urine and stools

• diarrhea

• nausea, vomiting

• skin discoloration

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

Methylene Blue Solution for injection

What is this medicine?

METHYLENE BLUE (METH uh leen bloo) is used to treat methemoglobinemia. This is a condition in which the blood loses its ability to carry oxygen through the body.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• cyanide poisoning

• glucose-6-phosphate dehydrogenase (G6PD) deficiency

• kidney disease

• an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• bupropion

• certain medicines for depression or anxiety

• clomipramine

• doxepin

• duloxetine

• fluoxetine

• MAOIs like Marplan, Nardil, and Parnate

• milnacipran

• mirtazapine

• rasagiline

• selegiline

• St. John's wort

• trazodone

• tryptophan

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• chest pain

• confusion

• dizziness

• headache

• increased sweating

• stomach pain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blue-green coloration of urine and stools

• nausea, vomiting

• skin discoloration

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.