Granisetron extended-release injection

September 30, 2017

Granisetron extended-release injection

What is this medicine?

GRANISETRON (gra NI se tron) is an antiemetic. It is used to prevent nausea and vomiting caused by chemotherapy.

How should I use this medicine?

This medicine is for injection under the skin. It is given by a health care professional in a hospital or clinic setting.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • confusion

  • constipation

  • dizziness

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • fever and chills

  • loss of balance or coordination

  • seizures

  • skin irritation or skin reaction

  • sweating

  • tightness in the chest

  • tremors

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • headache

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole

  • cisapride

  • dofetilide

  • dronedarone

  • pimozide

  • thioridazine

  • ziprasidoneThis medicine may also interact with the following medications:

  • certain medicines for depression, anxiety, or psychotic disturbances

  • fentanyl

  • linezolid

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • methylene blue (injected into a vein)

  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)

  • phenobarbital

  • tramadol

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • dry hard stool that will not pass out of your rectum

  • an unusual or allergic reaction to granisetron, ondansetron, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Updated:  

September 30, 2017