Ethacrynic Acid
Ethacrynate Sodium Solution for injection
What is this medicine?
ETHACRYNIC ACID (eth a KRIN ik AS id) is a diuretic. It helps you make more urine and to lose salt and excess water from your body. This medicine is used to treat edema, heart failure, or water retention.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
abnormal blood electrolytes
diarrhea or vomiting
gout
hearing problems
heart disease
kidney disease, small amounts of urine, or difficulty passing urine
liver disease
an unusual or allergic reaction to ethacrynic acid, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is injected into a vein. It is usually given by a health care professional in a hospital or a clinic.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
antiinflammatory drugs like indomethacin
certain antibiotics given by injection
diuretics
heart medicines like digoxin
hormones like cortisone, fludrocortisone, or hydrocortisone
lithium
medicines for diabetes
medicines for high blood pressure
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
You will be closely monitored while taking this medicine. It will lower your blood pressure and may increase your blood sugar. If you are diabetic your sugar will need to be checked.
This medication can make you feel confused, dizzy or lightheaded. Drinking alcohol can make this worse. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not sit or stand up quickly.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
blood in the urine or stools
blurred vision
dry mouth
fever or chills
hearing loss, ringing in the ears
irregular heartbeat
muscle cramps, pain or weakness
unusually weak or tired
vomiting or diarrhea
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
headache
loss of appetite
stomach upset, pain or nausea
unusual bleeding or bruising
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store vials at room temperature (59 and 86 degrees F). After mixing the injection solution use within 24 hours. Do not use if the solution is hazy or cloudy. Throw away any unused injection solution.
Ethacrynic Acid Oral tablet
What is this medicine?
ETHACRYNIC ACID (eth a KRIN ik AS id) is a diuretic. It helps you make more urine and to lose salt and excess water for your body. This medicine is used to treat edema, heart failure, or water retention.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
abnormal blood electrolytes
diarrhea or vomiting
gout
hearing problems
heart disease
kidney disease, small amounts of urine, or difficulty passing urine
liver disease
an unusual or allergic reaction to ethacrynic acid, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth. Follow the directions on the prescription label. This medicine should be taken after a meal. Do not take your medicine more often than directed. Remember that you will pass more urine after taking this medicine. Do not take your medicine at a time of day that will cause you problems.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
antiinflammatory drugs like indomethacin
certain antibiotics given by injection
diuretics
heart medicines like digoxin
hormones like cortisone, fludrocortisone, or hydrocortisone
lithium
medicines for diabetes
medicines for high blood pressure
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Check your blood pressure regularly. Ask your doctor or health care professional what your blood pressure should be, and when you should contact him or her. If you are diabetic, check your blood sugar as directed. Do not stop taking your medicine unless your doctor tells you to.
You may need to be on a special diet while taking this medicine. Ask your doctor. Also, ask how many glasses of fluids you need to drink each day. You must not get dehydrated.
This medication can make you feel confused, dizzy or lightheaded. Drinking alcohol can make this worse. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
blood in the urine or stools
blurred vision
dry mouth
fever or chills
hearing loss, ringing in the ears
irregular heartbeat
muscle cramps, pain or weakness
unusually weak or tired
vomiting or diarrhea
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
headache
loss of appetite
stomach upset, pain or nausea
unusual bleeding or bruising
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert