Etelcalcetide injection

What is this medicine?

ETELCALCETIDE (E tel KAL se tide) is used to treat high levels of parathyroid hormone in patients with chronic kidney disease on dialysis.

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reaction like skin rash, itching or hives, swelling of the face, lips, or tongue

• signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems

• signs of low calcium like fast heartbeat; muscle cramps or muscle pain; pain, tingling, numbness in the hands or feet; seizures

• signs of worsening heart failure like breathing problems; swelling in your legs and feet

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

• diarrhea

• headache

• nausea

• vomiting

What may interact with this medicine?

• cinacalcet

What if I miss a dose?

Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• heart disease

• history of stomach bleeding

• low levels of calcium in your blood

• seizures

• an unusual or allergic reaction to etelcalcetide, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

You may need blood work done while you are taking this medication.