Eliglustat oral capsules
Eliglustat oral capsules
What is this medicine?
ELIGLUSTAT (el i GLOO stat) is used for the long-term treatment of adults with Gaucher disease type I. Eliglustat is not used in certain people with Gaucher disease type 1. Your doctor will perform a test to make sure this medicine is right for you.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Do not take with grapefruit juice. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do no take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heart beat; palpitations; feeling faint or lightheaded, falls; breathing problems
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
headache
nausea
pain in the arms, legs, or back
stomach pain
tiredness
What may interact with this medicine?
Do not take this medicine with any of the following medications:
cisapride
dofetilide
dronedarone
grapefruit juice
pimozide
quinidine
quinine
ritonavir
saquinavir
tipranavir
thioridazine
ziprasidone
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for fungal infections like ketoconazole and itraconazole
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
colchicine
dabigatran
digoxin
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
ranitidine
rifampin
St. John's Wort
What if I miss a dose?
If you miss a dose, take the next dose at the usual time. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart disease
history of heart attack
history of irregular heartbeat
kidney disease
liver disease
an unusual or allergic reaction to eliglustat, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
Certain genetic factors may reduce the effect of this medicine. Your doctor may use genetic tests to determine treatment.
Updated:  
July 17, 2018