Drotrecogin Alfa Solution for injection

What is this medicine?

DROTRECOGIN ALFA (droe tre KOE gin AL fa) is used to treat life-threatening sepsis.

NOTE: Drotecogin alfa has been withdrawn from the market and is no longer available.

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose

aspirin and aspirin-like medicines
cilostazol
clopidogrel
dipyridamole
medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, heparin
pentoxifylline
ticlopidine

This does not apply.

This drug is given in a hospital or clinic and will not be stored at home.

They need to know if you have any of these conditions:

bleeding disorders
brain or spine surgery or injury
history of any bleeding event
low platelet count in the blood
liver disease
stroke
take medicines that treat or prevent blood clots
an unusual or allergic reaction to drotrecogin alfa, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

Your condition will be monitored carefully while you are receiving this medicine.

Updated:

March 22, 2017