Dexmedetomidine
Dexmedetomidine injection
What is dexmedetomidine injection?
DEXMEDETOMIDINE (Precedex®) is an anesthetic agent used to reduce anxiety and tension, and promote relaxation and sedation in patients needing a mechanical ventilator. Dexmedetomidine is administered to patients only by health care professionals in an intensive care or surgical area. Generic dexmedetomidine injections are not available.
What should my health care professional know before I receive dexmedetomidine?
They need to know if you have any of these conditions:
adrenal insufficiency
blood vessel disease
heart disease
kidney disease
liver disease
previous heart attack or stroke
an unusual or allergic reaction to dexmedetomidine, other anesthetics, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Dexmedetomidine is for injection into a vein. It is given by trained health care professionals in an intensive care or surgical area.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
Elderly patients over 65 years old may have a stronger reaction to this medicine and need smaller doses.
What if I miss a dose?
This does not apply.
What drug(s) may interact with dexmedetomidine?
alcohol
barbiturate medicines for inducing sleep or treating seizures (convulsions)
medicines for anxiety or sleeping problems, such as diazepam or temazepam
muscle relaxants
some medicines for hay fever and other allergies (antihistamines)
some medicines for depression or mental illness (antidepressants, phenothiazines)
some medicines for pain (narcotic analgesics, tramadol)
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking dexmedetomidine?
You will be closely monitored in an intensive care or surgical area during the administration of dexmedetomidine.
What side effects may I notice from receiving dexmedetomidine?
Side effects that you should report to your prescriber or health care professional as soon as possible:
confusion
decreased amount of urine passed
difficulty breathing, shortness of breath, or wheezing
dizziness, lightheadedness or fainting spells
slow heartbeat
fast or irregular heartbeat
fever, chills
palpitations
numbness or tingling in the hands or feet
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
anxiety, nervousness
blurred vision or other change in vision
diarrhea
dizziness
drowsiness
dry mouth or thirst
headaches
increased sweating
nausea or vomiting
pain or irritation at the injection site
stomach pain or cramps
Where can I keep my medicine?
This medicine is administered only by a health care professional and you will not use this medicine at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert