DRUGS AND SUPPLEMENTS

Cinoxacin

March 21, 2017

Cinoxacin capsules

What are cinoxacin capsules?

CINOXACIN (Cinobac®) is a quinolone antibiotic. This antibiotic is used to treat urinary tract infections. Generic cinoxacin capsules are available.

What should my health care professional know before I receive cinoxacin?

They need to know if you have any of these conditions:

  • kidney disease

  • liver disease

  • seizures (convulsions)

  • stomach problems

  • an unusual or allergic reaction to cinoxacin, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should this medicine be used?

Take cinoxacin capsules by mouth. Follow the directions on the prescription label. Swallow the capsules with a full glass of water. Although this medicine may be taken with meals, it is best to take cinoxacin on an empty stomach. Do not take with magnesium/aluminum containing antacids, sucralfate, Videx (didanosine), or with foods or other products containing calcium, iron, or zinc. Cinoxacin may be taken 2 hours before or 6 hours after these products. Cinoxacin should not be taken with a meal consisting of only milk, yogurt, calcium fortified juices, or other dairy products; however cinoxacin may be taken with a meal that contains these foods. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your health care provider even if you think your condition is better. Do not stop taking cinoxacin unless advised by your prescriber.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. This medication should be taken at regular intervals.

What drug(s) may interact with cinoxacin?

  • aluminum salts

  • antacids

  • caffeine

  • calcium salts

  • didanosine, ddI

  • doxercalciferol

  • iron supplements

  • magnesium salts

  • multivitamins containing calcium, iron, magnesium, or zinc

  • NSAIDs such as Advil®, Aleve®, ibuprofen, Motrin®, or naproxen

  • phenytoin or fosphenytoin

  • probenecid

  • sucralfate

  • theophylline

  • warfarin

  • zinc salts

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking cinoxacin?

Tell your health care provider if your symptoms do not improve in 2 to 3 days or if symptoms increase.

If you get severe or watery diarrhea, do not treat yourself. Call your prescriber or health care professional.

Cut down on or avoid drinks that contain caffeine. Cinoxacin can increase the stimulant effects of caffeine and cause heart, breathing, and other problems.

Keep out of the sun or wear protective clothing outdoors and use sunscreen 30 spf or higher. Do not use sun lamps or sun tanning beds or booths.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how cinoxacin affects you.

Antacids can make cinoxacin ineffective. If you get an upset stomach and want to take an antacid, make sure there is at least an interval of 2 hours since you last took cinoxacin or 6 hours before your next dose. Iron and zinc preparations can also make cinoxacin ineffective. Do not take multivitamins at the same time you take your cinoxacin capsules.

If you notice pain or swelling of a tendon or joint, stop taking cinoxacin. Call your healthcare provider immediately. Rest the affected area. Do not exercise or take cinoxacin again until your health care provider tells you to do so.

What side effects may I notice from receiving cinoxacin?

Side effects that you should report to your prescriber or health care professional as soon as possible:

  • difficulty breathing

  • fever

  • increased sensitivity to the sun or ultraviolet light

  • irregular heartbeat, palpitations, or chest pain

  • joint, muscle, or tendon pain

  • nervousness, restlessness, anxiety

  • severe stomach or abdominal pain

  • severe or watery diarrhea

  • seizures (convulsions)

  • skin rash or itching

  • swelling of the face or neck

  • vomiting

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • diarrhea (loose stools)

  • difficulty sleeping

  • dizziness, drowsiness

  • headache

  • nausea

  • stomach upset

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15—30 degrees C (59—86 degrees F). Keep the container tightly closed. Throw away any unused medicine after the expiration date.

Updated:  

March 21, 2017

Sources:  

U.S. FDA-approved Package Insert