What is this medicine?
CANAKINUMAB is used to treat certain types of arthritis in children. It is also used to treat rare periodic fever syndromes including cryopyrin-associated periodic syndromes (CAPS), tumor necrosis factor receptor associated periodic syndrome (TRAPS), hyperimmunoglobulin D syndrome (HIDS)/mevalonate kinase deficiency (MKD), and familial Mediterranean fever (FMF). This medicine is not a cure.
How should I use this medicine?
This medicine is for injection under the skin. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
feeling faint or lightheaded, falls
signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
pain, redness, or irritation at site where injected
What may interact with this medicine?
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
steroid medicines like prednisone or cortisone
What if I miss a dose?
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
human immunodeficiency virus (HIV) infection
immune system problems
infection (especially a virus infection like chickenpox, cold sores, or herpes)
lung or breathing disease, like asthma
an unusual or allergic reaction to canakinumab, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medicine.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This medicine may increase your risk of getting an infection. Try to avoid being around people who are sick. Tell your doctor or health care professional if you are around anyone with measles or chickenpox or if you develop sores or blisters that do not heal properly.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
September 30, 2017