Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine Oral Solution
Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine Oral Solution
What is this medicine?
ACETAMINOPHEN; DEXTROMETHORPHAN; GUAIFENESIN; PHENYLEPHRINE (a set a MEE noe fen; dex troe meth OR fan; gwye FEN e sin; fen il EF rin) is a combination of a pain reliever, a cough suppressant, an expectorant, and a decongestant. It is used to treat the aches and pains, fever, cough, and congestion of a cold. This medicine will not treat an infection.
How should I use this medicine?
Take this medicine by mouth. Follow the directions on the package label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain, tightness
dizziness, nervousness, or sleeplessness
fast, irregular heartbeat
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
yellowing of skin or eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
drowsiness
dry eyes, mouth
loss of appetite
stomach upset
What may interact with this medicine?
Do not take this medicine with any of the following medications:
cocaine
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
stimulant medicines like dextroamphetamine and others
This medicine may also interact with the following medications:
alcohol
atomoxetine
atropine
bretylium
digoxin
furazolidone
imatinib
isoniazid
linezolid
maprotiline
mecamylamine
midodrine
medicines for chest pain like isosorbide dinitrate, nitroglycerin
medicines for depression, anxiety, or psychotic disturbances
medicines for sleep during surgery
other medicines for cold, cough or allergy
other medicines with acetaminophen
procarbazine
St. John's Wort
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
heart disease
high blood pressure
if you often drink alcohol
liver disease
taken a MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
thyroid disease
trouble passing urine
an unusual or allergic reaction to acetaminophen, dextromethorphan, guaifenesin, phenylephrine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Let your doctor know if you have pain, nasal congestion, or cough that gets worse or lasts for more than 7 days. Call your doctor if you have a sore throat that gets worse or lasts for more than 2 days. Or, if you have a sore throat with a fever, rash, headache, nausea, or vomiting, see your doctor.
Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.
If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
Updated:  
July 17, 2018