Amprenavir
Amprenavir Oral capsule
What is this medicine?
AMPRENAVIR (am PREN a veer) is an antiretroviral drug. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
NOTE: This drug is discontinued in the United States. Patients taking Amprenavir should contact their prescriber regarding discontinuation and alternative therapies.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
hemophilia
liver disease
an unusual or allergic reaction to amprenavir, fosamprenavir, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food, but do not take it with a high fat meal. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose by more than 4 hours, wait and take the next dose at the regular time. But, if you miss a dose by less than 4 hours, take your missed dose right away. Then take your next dose at the regular time. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
astemizole
bepridil
cisapride
delavirdine
dofetilide
flecainide
female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
medicines for cholesterol like atorvastatin, cerivastatin, lovastatin, simvastatin
midazolam
pimozide
propafenone
ranolazine
red yeast rice
rifampin
rifapentine
triazolam
St. John's wort
vitamin E supplements
This medicine may also interact with the following medications:
amiodarone
antacids
cyclosporine
dexamethasone
fluticasone
lidocaine
medicines for depression, anxiety, or psychotic disturbances
medicines for fungal infections like ketoconazole and itraconazole
medicines for blood pressure like amlodipine, diltiazem, verapamil
medicines for seizures
methadone
other medicines for HIV
quinidine
rapamycin
rifabutin
sildenafil
sirolimus
tacrolimus
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills, patches, rings, or injections may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine contains large amounts of vitamin E. Do not take vitamin supplements that have vitamin E while you are taking this medicine.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste
depressed mood
diarrhea
increased hunger or thirst
increased urination
nausea, vomiting
stomach pain
tingling around the mouth
unusually weak or tired
weight gain around waist, back, or thinning of face, arms, legs
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Amprenavir Oral solution
What is this medicine?
AMPRENAVIR (am PREN a veer) is an antiretroviral drug. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
NOTE: This drug is discontinued in the United States. Patients taking Amprenavir should contact their prescriber regarding discontinuation and alternative therapies.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
hemophilia
if you are of Asian, Eskimo, or Native American descent
if you frequently drink alcohol containing drinks
kidney disease
liver disease
an unusual or allergic reaction to amprenavir, fosamprenavir, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take this medicine with or without food, but do not take it with a high fat meal. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose by more than 4 hours, wait and take the next dose at the regular time. But, if you miss a dose by less than 4 hours, take your missed dose right away. Then take your next dose at the regular time. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
alcohol or any product that contains alcohol
astemizole
bepridil
cisapride
disulfiram
dofetilide
flecainide
female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
medicines for cholesterol like atorvastatin, cerivastatin, lovastatin, simvastatin
metronidazole
midazolam
pimozide
propafenone
ranolazine
red yeast rice
rifampin
rifapentine
ritonavir oral solution
triazolam
St. John's wort
vitamin E supplements
This medicine may also interact with the following medications:
amiodarone
antacids
cyclosporine
dexamethasone
fluticasone
lidocaine
medicines for depression, anxiety, or psychotic disturbances
medicines for fungal infections like ketoconazole and itraconazole
medicines for blood pressure like amlodipine, diltiazem, verapamil
medicines for seizures
methadone
other medicines for HIV
quinidine
rapamycin
rifabutin
sildenafil
sirolimus
tacrolimus
warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills, patches, rings, or injections may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine contains large amounts of vitamin E. Do not take vitamin supplements that have vitamin E while you are taking this medicine.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing difficulties
nausea, vomiting, unusual stomach upset or pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
trouble passing urine or change in the amount of urine
unusually fast heart rate
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in taste
depressed mood
diarrhea
increased hunger or thirst
tingling around the mouth
weight gain around waist, back, or thinning of face, arms, legs
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert