Acetaminophen; Diphenhydramine oral powder
Acetaminophen; Diphenhydramine oral powder
What is this medicine?
ACETAMINOPHEN; DIPHENHYDRAMINE (a set a MEE noe fen; dye fen HYE dra meen) is a pain reliever antihistamine combination. It is used to treat pain and help you fall to sleep.
How should I use this medicine?
Place this medicine on the tongue and then drink a glass of water. Or, mix the powder into a glass of water or other drink and then drink it. Follow the directions on the package or prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children under 12 years of age.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
confused, agitated, nervous
fever gets worse or lasts more than 3 days
irregular or fast heartbeat
sore throat lasts more than 2 days
tremor
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation, diarrhea
drowsy
headache
loss of appetite
nausea, stomach upset
What may interact with this medicine?
Do not take this medicine with any of the following medications:
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
alcohol
barbiturates, like phenobarbital
imatinib
isoniazid
medicines for bladder spasm like oxybutynin, tolterodine
medicines for blood pressure
medicines for depression, anxiety, or psychotic disturbances
medicines for movement abnormalities or Parkinson's disease
medicines for sleep
other medicines for cold, cough or allergy
other medicines with acetaminophen
some medicines for the stomach like chlordiazepoxide, dicyclomine
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
asthma or lung disease
glaucoma
high blood pressure or heart disease
if you often drink alcohol
liver disease
pain or difficulty passing urine
prostate trouble
ulcers or other stomach problems
an unusual or allergic reaction to acetaminophen, diphenhydramine, other medicines foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Tell your doctor if your symptoms do not improve or if they get worse.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.
If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
Updated:  
July 17, 2018