Repetitive transcranial magnetic stimulation
Natural Standard Monograph, Copyright © 2013 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
Cortical modulation, magnet therapy, magnetic stimulation, neuropsychology, repetitive transcranial magnetic stimulation, rTMS.
Repetitive transcranial magnetic stimulation (rTMS) was developed by scientists in the 1980s as a tool for neurodiagnosis, nerve fiber study and the development of a functional brain map.
In the late 1980s, scientists started to use repetitive transcranial magnetic stimulation for the treatment of depression.
Over time, the use of rTMS has expanded and is currently not only used for the treatment of depression, but also to treat Parkinson's disease, auditory hallucination schizophrenia, tinnitus, migraines, eating disorders, obsessive compulsive disorder as well as other mood disorders.
rTMS is a more specific form of magnet therapy. Magnet therapy is the use of magnets to provide health benefits. rTMS uses a coil rather than a magnet to produce an electrical current and is specifically used on the scalp. Magnet therapy can generally be preformed on any part of the body affected by a specific ailment.
Repetitive transcranial magnetic stimulation is a procedure in which electrical activity in the brain is influenced by a pulsed magnetic field generated by brief current pulses through figure eight coils of wire. These wires are encased in plastic and held close to the scalp. The location of the device allows for stimulation of specific areas of the cortex (the surface of the brain).
rTMS is non invasive and requires no anesthesia. Few patients report any serious side effects. Mild side effects include headache and the perception of unwanted noise. These problems usually are treated with acetaminophen (Tylenol) and ear plugs respectively.
Depression is thought to be caused by a disturbance in activity in the frontal cortex of the brain. When the rTMS device is held close to the scalp, it allows for the non-invasive induction of a current of neurons. This induction is hypothesized to down regulate beta-adrenergic receptors and to subsequently increase the levels of dopamine and serotonin in the brain. While reported to be safe and painless, some patients do experience a headache, which typically resolves in a few hours and can be treated with acetaminophen.
Based on one randomized control trial, rTMS has been proven to be effective in the treatment of treatment resistant depression. An additional study examined the effect of rTMS on depression in adolescent patients. rTMS again proved to be effective and safe in this randomized control trial. Further research is being conducted as to whether rTMS has equal efficacy in the other areas of use.
rTMS is non invasive and requires no anesthesia. Few patients report any serious side effects. Mild side effects include headache and the perception of unwanted noise. These problems usually are treated with acetaminophen (Tylenol®) and ear plugs respectively.
This information has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Bretlau LG, Lunde M, Lindberg L, et al. Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatment-resistant major depression: a double-blind, randomised, sham-controlled trial. Pharmacopsychiatry. 2008 Mar;41(2):41-7. View Abstract
Fitzgerald PB, Benitez J, deCastella A, et al. A randomized, controlled trial of sequential bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression. Am J Psychiatry. 2006 Jan;163(1):88-94. View Abstract
Fitzgerald PB, Daskalakis ZJ. The use of repetitive transcranial magnetic stimulation and vagal nerve stimulation in the treatment of depression. Curr Opin Psychiatry. 2008 Jan;21(1):25-9. View Abstract
Jorge RE, Moser DJ, Acion L, et al. Treatment of vascular depression using repetitive transcranial magnetic stimulation. Arch Gen Psychiatry. 2008 Mar;65(3):268-76. View Abstract
Khedr EM, Rothwell JC, Ahmed MA, et al. Effect of daily repetitive transcranial magnetic stimulation for treatment of tinnitus: comparison of different stimulus frequencies. J Neurol Neurosurg Psychiatry. 2008 Feb;79(2):212-5. View Abstract
Landgrebe M, Binder H, Koller M, et al. Design of a placebo-controlled, randomized study of the efficacy of repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus. BMC Psychiatry. 2008 Apr 15;8:23. View Abstract
Lee SL, Abraham M, Cacace AT, et al. Repetitive transcranial magnetic stimulation in veterans with debilitating tinnitus: a pilot study. Otolaryngol Head Neck Surg. 2008 Mar;138(3):398-9. PMID: View Abstract
Loo C, McFarquhar T, Walter G. Transcranial magnetic stimulation in adolescent depression. Transcranial magnetic stimulation in adolescent depression. Australas Psychiatry. 2006 Mar;14(1):81-5. View Abstract
Walpoth M, Hoertnagl C, Mangweth-Matzek B, et al. Repetitive transcranial magnetic stimulation in bulimia nervosa: preliminary results of a single-centre, randomised, double-blind, sham-controlled trial in female outpatients. Psychother Psychosom. 2008;77(1):57-60. View Abstract
Copyright © 2013 Natural Standard (www.naturalstandard.com)
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
March 22, 2017