Gastric polyps are abnormal growths on the inner lining of your stomach. Most are harmless and don’t cause symptoms. But some of them turn into cancer.
Your stomach is the organ that receives chewed-up food. The stomach contains acid. It kills many of the bacteria in swallowed food. It also contains juices that aid in digestion. The innermost layer of the stomach has a lining of cells called the epithelium. Most gastric polyps come from an abnormal growth of cells in a section of the epithelium.
Gastric polyps are not cancerous. But some may turn into cancer. There are many types of gastric polyps. They happen for different reasons. Some have little or no risk of becoming cancer. Others have a higher risk of turning into cancer.
Abnormal tissue growth is called dysplasia. Gastric polyps with dysplasia are the ones most likely to turn into cancer.
In the U.S., fundic gland polyps are the most common type of gastric polyp. The second most common are hyperplastic polyps. Hyperplastic polyps are common in places that have a higher rate of H. pylori infections. Gastric polyps are more common in older adults.
Gastric polyps can happen for different reasons. Anything that causes your stomach cells to grow abnormally can lead to this problem. Some of the causes of gastric polyps include:
- Chronic inflammatory stomach issues
- H. pylori infection
- Pernicious anemia
- Stomach erosion. This can happen from an ulcer.
- Using proton-pump inhibitor medicines. These include omeprazole.
Some of these causes may increase your risk for certain types of gastric polyps, but not others. For instance, an H. pylori infection raises your risk for hyperplastic polyps. Proton-pump inhibitor medicines may increase your risk for fundic gland polyps.
Genetics also play a role. You may also have a higher risk of gastric polyps if they run in your family.
Most gastric polyps don’t cause any symptoms. Most people learn they have a gastric polyp after having a test for another reason. This test is called an upper endoscopy. In this test, a thin tube with a tiny camera looks into your stomach.
Your chance of symptoms depends on the type of polyp you have. Larger polyps may be more likely to cause the following symptoms:
- Stomach pain
- Symptoms from a polyp that has broken open (ulcerated). These may include bleeding in the stomach and anemia.
- Symptoms from stomach blockage. These may include weight loss or intense vomiting.
Gastric polyps that become cancer may cause other symptoms.
Most gastric polyps are diagnosed during an upper endoscopy.
To diagnose the type of polyp, your healthcare provider will do a biopsy. In a biopsy, you will have a sample of the gastric polyp and nearby tissue taken out. This happens during an endoscopy. A specialist then looks at the sample under a microscope and can then diagnose the type of polyp you have. Your healthcare provider may also ask about your health history and give you an exam. This can sometimes give helpful clues about the type of polyp.
In some cases, cancerous growths look like gastric polyps on an upper endoscopy. Because of this, some people who are told they have a gastric polyp at first may actually have cancer.
Treatment for gastric polyps varies. Your treatment may depend on:
- Polyp type
- Polyp size
- Polyp shape
- Polyp location
- How many polyps you have
- Your symptoms
- Your other risk factors for stomach cancer. These include your age and smoking history.
A fundic gland polyp has only a small chance of becoming cancer. At first, your healthcare provider will biopsy the polyp. Then a specialist can check for early signs that the polyp might become cancer. He or she will look for signs of dysplasia.
If the polyp doesn’t look like it may become cancer, you may not need any treatment. If you have a dysplastic polyp, you will likely have it removed. If you have a very large polyp, you also may need to have it taken out.
If you have another type of gastric polyp, such as a hyperplastic polyp, your treatment may be different. This type of polyp carries a higher risk for cancer. Again, your healthcare provider will want to biopsy the polyp and check for signs of cancer. You will likely need to have very large or dysplastic polyps removed. Even if your polyps don’t look dysplastic, your doctor may watch them. You may need to have more endoscopies.
If you have a carcinoid polyp (neuroendocrine), your treatment may include watching it or removing it. Your healthcare provider may remove it using endoscopy or surgery.
Adenomatous polyps have a high risk of turning into cancer. Because of this, your healthcare provider will likely want to remove them.
Your healthcare provider will remove any growth that becomes cancer. He or she will also take out any type of polyp with dysplasia. If the dysplasia or cancer has spread into nearby tissue, your healthcare provider may remove part of that tissue as well. Depending on how much it has spread, you may have this done through an endoscopy. Or you may need surgery to remove part of your stomach. Your healthcare provider will also likely remove any polyps that cause symptoms.
The main complication of gastric polyps is stomach cancer. The following is a list of some of the main types of gastric polyps and their cancer risk.
Type of gastric polyp
Risk of turning into cancer
Fundic gland polyps
Low, but higher in polyps with certain characteristics
Inflammatory fibroid polyps
Gastroneuroendocrine tumor polyps
Depends on the type
Gastrointestinal stromal tumor polyps
If you have multiple gastric polyps, this can also cause problems. For instance, familial adenomatous polyposis is a genetic condition. It causes polyps to grow all along your digestive tract. This leads to a very high risk for colon cancer.
Having your polyps removed can also cause complications. These include bleeding.
You may be able to lower your risk for new gastric polyps. For instance, your healthcare provider may tell you to stop using proton-pump inhibitor medicines if you have fundic polyps. You may be able to reduce your risk for hyperplastic polyps if you take an antibiotic for an H. pylori infection.
To lower your risk for problems from gastric polyps, see your healthcare provider as often as he or she suggests. Follow the care plan that he or she prescribes.
Call your healthcare provider if you have any symptoms that could be from a gastric polyp. These may include stomach pain or blood in your stool.
- Gastric polyps are abnormal growths on the lining of your stomach. Most are harmless and don’t cause symptoms. But some may turn into cancer.
- There are several types of gastric polyps. Your risk of cancer depends on the type of polyp you have.
- Your healthcare provider will likely do a biopsy of your polyp. This is done during an upper endoscopy. This can tell what type of polyp you have.
- Your treatment depends on the size, location, appearance, and type of polyp you have. If you have dysplastic polyps or cancerous growths, your healthcare provider will remove them.
- Your healthcare provider may do follow-up testing to check on your polyps.
Tips to help you get the most from a visit to your healthcare provider:
- Know the reason for your visit and what you want to happen.
- Before your visit, write down questions you want answered.
- Bring someone with you to help you ask questions and remember what your provider tells you.
- At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.
- Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.
- Ask if your condition can be treated in other ways.
- Know why a test or procedure is recommended and what the results could mean.
- Know what to expect if you do not take the medicine or have the test or procedure.
- If you have a follow-up appointment, write down the date, time, and purpose for that visit.
- Know how you can contact your provider if you have questions.
May 09, 2018
Gastric polyps. UpToDate.
Lehrer, Jenifer, MD,Sather, Rita, RN